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Chitosan derivatives are expected to be hygroscopic and moisturizing agents

July 06, 2023
The application results of the carboxymethyl chitosan quaternary ammonium salt developed by the Institute of Coastal Research of Yantai, Chinese Academy of Sciences as a hygroscopic moisturizer have recently been authorized by the national invention patent.
pharmaceutical intermediate

The patent utilizes the principle of active superposition and the method of substructure connection to insert the carboxymethyl group and the quaternary ammonium salt at the same time into the chitosan to improve the hygroscopicity and moisturizing activity, and to develop a chitosan having two kinds of hygroscopic and moisturizing active groups at the same time. derivative. The moisture absorption and moisturizing properties of these derivatives are obviously enhanced and they are expected to be developed as alternatives to hyaluronic acid.


The resulting carboxymethyl chitosan quaternary ammonium salt has a wide range of applications. It is commonly used as a biocompatible and biodegradable material in various fields, including biomedical, pharmaceutical intermediate, and cosmetic industries. Its antimicrobial properties make it useful in wound healing, drug delivery, and personal care products. Additionally, it can be used as a flocculant in water treatment processes and as a stabilizer in food and beverage industries.

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